ANTIMONY CHLORIDE SKIN

Material Safety Data Sheet (MSDS) for antimony Tichloride.Not combustible.

The Physical and Theoretical Chemistry Laboratory of Oxford University (2005).

Public Health Service in collaboration with U.S.

ATSDR - Agency for Toxic Substances and Disease Registry (1992).

IARC Monographs on the Evaluation of Carcinogenic Risks to Humans.

International Agency for Research on Cancer (2014).

Acton, MA: Publishing Sciences Group, Inc. CCIS Volume 141, edition expires Aug, 2009.

Poon R, Chu I, Lecavalier P, Valli VE, Foster W, Gupta S, Thomas B: Effects of antimony on rats following 90-day exposure via drinking water.

A physician may need to examine the area if irritation or pain persists.

Following dermal exposure, remove contaminated clothing and wash exposed area thoroughly with soap and water. In case of eye exposure, irrigate exposed eyes with copious amounts of room temperature water for at least 15 minutes. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. Administer oxygen and assist ventilation as required. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Following inhalation exposure, move patient to fresh air. ( 4, 6)įollowing oral exposure to antimony, administer charcoal as a slurry (240 mL water/30 g charcoal).

ANTIMONY CHLORIDE SKIN

Skin or eye contact can cause pain and redness of the exposed surface. Dyspnea, headache, vomiting,cough, conjunctivitis, and bloody purulent discharge from nose can result from inhalation exposure. ( 6)Ībdominal pain, vomiting, diarrhea can result from inhalation of antimony. Cerebral oedema, coma, convulsions, and death are possible. Myocardial depression, vasodilation and fluid loss may cause shock with hypotension, electrolyte disturbances and acute renal failure. Increased blood pressure can also result from antimony poisoning. Alterations in pulmonary function and other effects including chronic bronchitis, chronic emphysema, inactive tuberculosis, pleural adhesions, and irritation can result from inhalation of antimony. Antimony poisoning can also lead to pneumoconiosis. Exposure can also occur through dermal or skin contact ( 6).ĭermal exposure to antimony can cause antimony spots (papules and pustules around sweat and sebaceous glands). ( 5)īreathing air, drinking water, and eating foods that contain antimony.

No indication of carcinogenicity (not listed by IARC). Some of the fecal antimony may represent unabsorbed antimony that is cleared from the lung via mucociliary action into the esophagus to the gastrointestinal tract. Antimony is excreted via the urine and feces. It is not known if these interactions are toxicologically significant. Antimony can covalently interact with sulfhydryl groups and phosphate, as well as numerous reversible binding interactions with endogenous ligands (e.g., proteins). Antimony is a metal and, therefore, does not undergo catabolism. Blood is the main vehicle for the transport of absorbed antimony to various tissue compartments of the body. The adrenal glands, lung, large intestine, trachea, cerebellum, and kidneys also contain relatively high levels of antimony. The hair and skin contain the highest levels of antimony. ( 2, 6, 1)Īntimony is widely distributed throughout the body. Moreover, the The cause of death is believed to be essentially the same as that in acute arsenic poisoning. The antidotal action of BAL depends on its ability to prevent or break the union between antimony and vital enzymes. However, some studies suggest that antimony combines with sulfhydryl groups including those in several enzymes important for tissue respiration. The mechanism of action of antimony remains unclear. It is possible that antimony affects circulating glucose by interfering with enzymes of the glycogenolysis and gluconeogenesis pathways. The inhalation data suggest that the myocardium is a target of antimony toxicity. Predicted LC-MS/MS Spectrum - 40V, Negative Predicted LC-MS/MS Spectrum - 20V, Negative Predicted LC-MS/MS Spectrum - 10V, Negative Predicted LC-MS/MS Spectrum - 40V, Positive Predicted LC-MS/MS Spectrum - 20V, Positive Predicted LC-MS/MS Spectrum - 10V, Positive antimony molecular entity ( CHEBI:74856 ).These are inorganic compounds in which the largest halogen atom is Chlorine, and the heaviest metal atom is a metalloid. Belongs to the class of inorganic compounds known as metalloid chlorides.

Antimony chloride